Scientific References

The company is not endorsed by, sponsored by, or affiliated with any of these organizations
1.
Evaluation of the safety, tolerability and plasma vitamin D response to long‑term use of patented transdermal vitamin D patches in healthy adults: a randomized parallel pilot study.
BMJ Nutrition, Prevention & Health – Pilot RCT showing healthy adults wearing vitamin D₃ patches (30,000 IU) achieved measurable serum increases and reduced deficiency rates from 23% to 0% over 8 weeks.
>> https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9813629/ ec.bioscientifica.com+2mybarriere.com+2sciencedirect.com+2pmc.ncbi.nlm.nih.gov+1researchgate.net+1
2.
Topical Delivery of Vitamin D₃: A Randomized Controlled Pilot Study**
International Journal of Biomedical Science (2014) – Trial involving 48 women; serum 25‑OHD rose from ~12 ng/mL to ~38 ng/mL over 3 months with topical vitamin D₃.
>> https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3976443/ pmc.ncbi.nlm.nih.gov+1researchgate.net+1researchgate.net
3.
A multistage double‑blind placebo‑controlled study to assess the safety and efficacy of transdermal vitamin D phosphate supplementation (TransVitD)**
Trials (Feb 2025) – Ongoing 12‑week double‑blind RCT (n≈100) testing a water‑soluble vitamin D phosphate patch. This trial explores both safety and increases in serum 25‑OH‑D at weeks 4 and 8.
>> https://pubmed.ncbi.nlm.nih.gov/ (Clinical Trials.gov NCT06098846) / BMC Trials journal pmc.ncbi.nlm.nih.gov+13 pmc.ncbi.nlm.nih.gov+13kcl.ac.uk+13
4.
In‑vitro/ex‑vivo delivery studies including vitamin D**
Peeking into the future: Transdermal patches for the delivery of… (ScienceDirect, 2021) – Lab research demonstrating successful delivery of vitamin D through skin models.
>> https://www.sciencedirect.com/science/article/pii/S2589936821000335
5.
A novel high-efficiency transdermal patch for combinational therapy of Alzheimer’s disease: Donepezil/vitamin B12-loaded nanofibers
Published in: Journal of Drug Delivery Science and Technology (2023)
>> https://www.sciencedirect.com/science/article/abs/pii/S1773224723008158
6.
Peeking into the future: Transdermal patches for the delivery of micronutrient supplements Metabolism Open, 2021
>> https://pubmed.ncbi.nlm.nih.gov/34337377/